High throughput physicochemical profiling for drug discoveryKERNS, Edward H.Journal of pharmaceutical sciences. 2001, Vol 90, Num 11, pp 1838-1858, issn 0022-3549Article

Biological assay challenges from compound solubility : strategies for bioassay optimizationLI DI; KERNS, Edward H.Drug discovery today. 2006, Vol 11, Num 9-10, pp 446-451, issn 1359-6446, 6 p.Article

Pharmaceutical profiling in drug discoveryKERNS, Edward H; LI DI.Drug discovery today. 2003, Vol 8, Num 7, pp 316-323, issn 1359-6446, 8 p.Article

Drug-Like Property Concepts in Pharmaceutical DesignLI DI; KERNS, Edward H; CARTER, Guy T et al.Current pharmaceutical design (Print). 2009, Vol 15, Num 19, pp 2184-2194, issn 1381-6128, 11 p.Article

Development and application of high throughput plasma stability assay for drug discoveryLI DI; KERNS, Edward H; YAN HONG et al.International journal of pharmaceutics. 2005, Vol 297, Num 1-2, pp 110-119, issn 0378-5173, 10 p.Article

Pharmaceutical profiling method for lipophilicity and integrity using liquid chromatography-mass spectrometryKERNS, Edward H; LI DI; PETUSKY, Susan et al.Journal of chromatography. B. 2003, Vol 791, Num 1-2, pp 381-388, issn 1570-0232, 8 p.Article

Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC-MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC-MSLI DI; KERNS, Edward H; LI, Susan Q et al.International journal of pharmaceutics. 2007, Vol 335, Num 1-2, pp 1-11, issn 0378-5173, 11 p.Article

Combined application of parallel artificial membrane permeability assay and Caco-2 permeability assays in drug discoveryKERNS, Edward H; DI, Li; PETUSKY, Susan et al.Journal of pharmaceutical sciences. 2004, Vol 93, Num 6, pp 1440-1453, issn 0022-3549, 14 p.Article

DRUG DISCOVERY INTERFACE: Comparison of Blood―Brain Barrier Permeability Assays: In Situ Brain Perfusion, MDR1-MDCKI and PAMPA-BBBLI DI; KERNS, Edward H; BEZAR, Ian F et al.Journal of pharmaceutical sciences. 2009, Vol 98, Num 6, pp 1980-1991, issn 0022-3549, 12 p.Article

Rapid, automated screening method for enzymatic transformations using a robotic system and supercritical fluid chromatographyLI DI; MCCONNELL, Oliver J; KERNS, Edward H et al.Journal of chromatography. B. 2004, Vol 809, Num 2, pp 231-235, issn 1570-0232, 5 p.Article

High throughput artificial membrane permeability assay for blood-brain barrierDI, Li; KERNS, Edward H; FAN, Kristi et al.European journal of medicinal chemistry. 2003, Vol 38, Num 3, pp 223-232, issn 0223-5234, 10 p.Article

High throughput microsomal stability assay for insoluble compoundsLI DI; KERNS, Edward H; LI, Susan Q et al.International journal of pharmaceutics. 2006, Vol 317, Num 1, pp 54-60, issn 0378-5173, 7 p.Article

Hybrid triple quadrupole-linear ion trap mass spectrometry in fragmentation mechanism studies : application to structure elucidation of buspirone and one of its metabolitesZHANG, Mei-Yi; PACE, Nadia; KERNS, Edward H et al.Journal of mass spectrometry. 2005, Vol 40, Num 8, pp 1017-1029, issn 1076-5174, 13 p.Article

Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT₆ ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 12, pp 3214-3216, issn 0960-894X, 3 p.Article

Integrated high capacity solid phase extraction-MS/MS system for pharmaceutical profiling in drug discoveryKERNS, Edward H; KLEINTOP, Teresa; LITTLE, David et al.Journal of pharmaceutical and biomedical analysis. 2004, Vol 34, Num 1, pp 1-9, issn 0731-7085, 9 p.Article

Evidence-based approach to assess passive diffusion and carrier-mediated drug transportLI DI; ARTURSSON, Per; LENNERNÄS, Hans et al.Drug discovery today. 2012, Vol 17, Num 15-16, pp 905-912, issn 1359-6446, 8 p.Article

1-Sulfonylindazoles as potent and selective 5-HT₆ ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 9, pp 2413-2415, issn 0960-894X, 3 p.Article

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT₆ ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 3929-3931, issn 0960-894X, 3 p.Article

Development of a liquid chromatography/tandem mass spectrometry method for the quantitation of acetylcholine and related neurotransmitters in brain microdialysis samplesZHANG, Mei-Yi; HUGHES, Zoë A; KERNS, Edward H et al.Journal of pharmaceutical and biomedical analysis. 2007, Vol 44, Num 2, pp 586-593, issn 0731-7085, 8 p.Article

Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT₆ antagonistsLIU, Kevin G; ROBICHAUD, Albert J; SMITH, Deborah L et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 1, pp 650-662, issn 0968-0896, 13 p.Article

Experimental design on single-time-point high-throughput microsomal stability assayDI, Li; KERNS, Edward H; NING GAO et al.Journal of pharmaceutical sciences. 2004, Vol 93, Num 6, pp 1537-1544, issn 0022-3549, 8 p.Article